Isoform-specific and signaling-dependent propagation of acute myeloid leukemia by Wilms tumor 1
Summary: Acute myeloid leukemia (AML) is caused by recurrent mutations in members of the gene regulatory and signaling machinery that control hematopoietic progenitor cell growth and differentiation.Here, we show that the transcription gorra artesanal factor WT1 forms a major node in the rewired mutation-specific gene regulatory networks of multipl